ReFissa is the first and only tretinoin that has exactly what you need to treat fine facial wrinkles in patients with normal to dry skin:
0.05% strength, clinically-proven efficacy1
Moisturizing emollient base that helps to minimize the redness and overdrying often caused by acne retinoids1
Fragrance-free formulation to further reduce the potential for allergic or additional irritation that can be caused by added perfumes2
Reference:
1. Data on file, ZO® Skin Health.
2. Common Scents: Fragrances Trigger Contact Dermatitis.
Modern Medicine. http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=595915.
Accessed May 21, 2009.
ReFissa 0.05% is indicated for mitigation (palliation) of fine facial wrinkles, mottled hyperpigmentation and tactile roughness in patients who use a comprehensive skin care and sunlight avoidance program (including sunscreen). ReFissa does not eliminate wrinkles, repair sun damaged skin, reverse photo-aging or restore more youthful or younger skin. Do not use if the patient is taking drugs known to be photosensitizers, pregnant, attempting pregnancy, or nursing. ReFissa, early in treatment, may cause redness, itching, burning, stinging and peeling. If the degree of irritation warrants, patient should be advised to use less medication and decrease the frequency of application. If still significant, patient should be advised to discontinue use. Please see full Prescribing Information. ReFissa is a registered trademark of ZO® Skin Health. © 2021 ZO® Skin Health. All rights reserved.
SM 1321-20 REV00
