Welcome to ReFissa® for Professionals

ReFissa is the first and only tretinoin that has exactly what you need to treat fine facial wrinkles in patients with normal to dry skin:

0.05% strength, clinically-proven efficacy1

Moisturizing emollient base that helps to minimize the redness and overdrying often caused by acne retinoids1

Fragrance-free formulation to further reduce the potential for allergic or additional irritation that can be caused by added perfumes2

1. Data on file, ZO® Skin Health.
2. Common Scents: Fragrances Trigger Contact Dermatitis. Modern Medicine. http://www.modernmedicine.com/modernmedicine/article/articleDetail.jsp?id=595915. Accessed May 21, 2009.